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Advances in Dental Research
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Adv Dent Res 13:57-66, June, 1999
© 1999 SAGE Publications

Soft Tissue and Epithelial Models

J.A. Jansen

Department of Biomaterials College of Dental Science Medical Faculty University of Nijmegen PO Box 9101 6500 HB Nijmegen, The Netherlands

E.T. Den Braber

Department of Biomaterials College of Dental Science Medical Faculty University of Nijmegen PO Box 9101 6500 HB Nijmegen, The Netherlands

X.F. Walboomers

Department of Biomaterials College of Dental Science Medical Faculty University of Nijmegen PO Box 9101 6500 HB Nijmegen, The Netherlands

J.E. De Ruijter

Department of Biomaterials College of Dental Science Medical Faculty University of Nijmegen PO Box 9101 6500 HB Nijmegen, The Netherlands

The applicability of a biomaterial for the manufacturing of oral implants is determined by its physicochemical and geometric surface properties. Research, therefore, is concerned with the cellular reactions that occur when an implant material comes into contact with body tissues. For permucosal oral implants, this involves both the reaction of bone and gingival cells. In vitro cell culturing-including the use of various analytical techniques like light microscopy, scanning and transmission electron microscopy, confocal laser scanning microscopy, and digital image analysis-is a good tool whereby investigators can obtain more insight into the relevant components of implant-tissue adhesion. In the current overview, the role of cell models in oral implant research is discussed, specifically with reference to responses of epithelial cells and fibroblasts.

Key Words: Fibroblast • epithelial cell • in vitro • permucosal • implant.

Advances in Dental Research, Vol. 13, No. 1, 57-66 (1999)
DOI: 10.1177/08959374990130011601
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